Clinical Trials

 The WHO Solidarity Trial aims to generate evidence-based information about promising drug candidates in the treatment of hospitalized COVID-19 patients.

The multicenter study in southern Germany is coordinated by Prof. Susanne Herold, PhD who is also the deputy speaker of the German part of this WHO Trial.

 

In collaboration with the DZL

  • GI-COVID - Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) Inhalation to prevent ARDS in COVID-19 pneumonia

The scope of this trial is to improve host defense of the lung and at the same time drive repair of the injured organ in hospitalized patients with COVID-19 pneumonia by inhalation of granulocyte-macrophage colony stimulating factor (GM-CSF; Molgramostim), a cytokine that has been shown to exert both of these effects in the lung. This study is funded by the BMBF as part of the "Nationales Forschungsnetz zoonotische Infektionskrankheiten"

read more (in german)

 

  • GI-Hope - https://clinicaltrials.gov/ct2/show/NCT02595060?term=GI+HOPE&rank=1

    This trial evaluates efficacy and safety of inhaled molgramostim (rhGM-CSF) in 45 patients with community-associated pneumonia (CAP)-related acute respiratory distress syndrome (ARDS).
    A third of the patients will receive 150 mcg inhaled molgramostim, another third 450 mcg and the remaining third will receive inhaled placebo for 3 days. The patients will be followed for 28 days.

read more (in german)

In collaboration with the German Center for Infection Research DZIF

  • R-Net 
    Das R-Net Projekt ist eine prospektive Beobachtungsstudie, in der über einen 4-Jahreszeitraum mikobiologische Resistenzdaten, genomische Daten, epidemiologische und klinische Daten sowie Daten zum Antibiotikaverbrauch erhoben werden, um belastbare Aussagen zur Resistenzentwicklung wichtiger Infektionserreger und ihrer Bedeutung für das deutsche Gesundheitssystem zu ermöglichen.
  • BLOOMY.COM
    Blutstrominfektionen verursacht durch multiresistente Bakterien - Multizentrische Studie über Bestimmungsgründe des Therapieerfolges

 

Biomaterial collection